| Name: |
Advanced Organic Synthesis |
| Catalog Number: |
411005Y |
Hours/Credits: |
40/2 |
| Prerequisite(s): |
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General Organic Chemistry
The course is designed for the students who should have organic chemistry background. It is suitable for graduate students of chemistry, especially for organic chemistry related students. |
| Course Description: |
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1. Develop a fundamental understanding of carbon-carbon single and double bond formation.
2. Develop a fundamental understanding of highly stereoselective reactions and their applications in complex syntheses.
3. Determine which strategic bond constructions can be used most effectively to obtain synthetic targets with high selectivity.
4. Become adept at identifying strengths and weaknesses of particular methods, and determine which one will be optimal for particular synthetic operations. |
| Course Content: |
|
Chapter 1 Alkyllation of nucleophilic carbon; enolates and enamines
Chapter 2 Reactions of carbon nucleophiles with carbonyl groups
Chapter 3 Functional group interconversion by nucleophilic substitution
Chapter 4 Electrophilic addition to double or triple bonds.
Chapter 5 Oxidation
Chapter 6 Reduction
Chapter 7 Pericyclic reactions
Chapter 8 Synthetic analysis and design |
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