| Name: |
Bioprocess Engineering |
| Catalog Number: |
422010Y |
Hours/Credits: |
40/2 |
| Prerequisite(s): |
|
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| Course Description: |
|
The course is the professional course of the post graduates of chemical engineering and biological chemistry. The post graduates of chemistry and biology can select the course as optional course. After the course is studied, students should grasp the concepts and methods of bio-process engineering. |
| Course Content: |
|
Chapter 1 What is a bioprocess engineer?
What is bioprocess engineer; The story of penicillin: how biologists and engineers work together; Regulatory constraints in bioprocess
Chapter 2 Engineering principles for bioprocesses
Operating considerations for bioreactors for suspension and immobilized cultures; Biocatalytic process improvement; Cell growth kinetics; The choice of the bioreactor and process control
Chapter 3 Applications to nonconventional biological systems
Bioprocess considerations in using animal cell cultures; Bioprocess considerations in using plant cell cultures; Utilizing genetically engineered organisms; Biosensor; Medical applications of bioprocess engineering; Mixed cultures
Chapter 4 Biological reaction and separation processes
The diversity of microbial metabolism; Industrial microorganisms and their products; Metabolic engineering; Culture media design; Starch sugar manufacturing process; Oxygen transfer and control of dissolved oxygen; Fed-batch fermentation; Fermentation process based on in situ product removal (ISPR) separation and purification process of some products such as organic acids, antibiotics, vitamins, and amino acids; Purification of the enzyme and protein drugs
Chapter 5 Bioprocess engineering application and process design
Penicillin production process and the development of semi-synthetic penicillin; Lactic acid, succinic acid fermentation technology; The operation of the production process software; Process calculation; process design and equipment selection; The development of the bioreactor and the manufacturers; Introduction of well-known bio-chemical laboratories and enterprises |
| TextBooks: |
|
Micheal L. Shular (author), Fikret kargi (author), Tao Chen (translator) and Xueming Zhao (translator). Bioprocess engineering: Basic concepts. Chemical Industry Press, Beijing, 2008 (in Chinese) |
| Reference: |
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Juntang Yu, Xiaoxuan Tang, Xingyan Wu, Yourong Li and Qingping Jin. Newly edited biological technology. Chemical Industry Press, Beijing, 2003 (in Chinese) |
